Organizing pneumonia associated with multicentric reticulohistiocytosis

Organizing pneumonia associated with multicentric reticulohistiocytosis

Organizing pneumonia (OP) is a clinicopathological entity that occurs idiopathically or in association with several conditions such as connective tissue diseases. Multicentric reticulohistiocytosis (MRH) is a systemic disease characterized by polyarthritis and mucocutaneous lesions, but lung involvement is uncommon. We report a patient with MRH associated with OP. This case may be of interest w...

Progressive multicentric reticulohistiocytosis.

Multicentric Reticulohistiocytosis Associated with Liver Carcinoma: Report of a Case

We report a unique case of multicentric reticulohistiocytosis (MRH) associated with liver carcinoma. A 61-year-old man presented with a 4-month history of nonpruritic, generalized, ruby-red papules and nodules, accompanied by fever, joint swelling and difficulty in swallowing. Skin histology showed polymorphic histiocyte infiltration with typical 'ground glass' cytoplasm. Further immunohistoche...

Multicentric Reticulohistiocytosis with Dermatomyositis-like Eruptions

A 68-year-old man presented with polyarthritis, proximal muscle weakness, and erythema of the face, arms, neck, and anterior chest that resembled the V-neck sign. Initially, dermatomyositis (DM) was considered because of the erythema, polyarthritis, and muscle weakness. He also had mediastinal and hilar lymphadenopathy on contrast-enhanced computed tomography. Unexpectedly, a biopsy of the fore...

Multicentric Reticulohistiocytosis Treated Successfully with Etanercept

Multicentric reticulohistiocytosis (MRH) is an uncommon systemic disease of unknown aetiology, which is characterized by the presence of papulonodular lesions, and is caused by the proliferation of histiocytes associated with arthritis. There are only just 200 cases described in the scientific literature. It can behave like a paraneoplasia and may be malignant in a quarter of the patients. We w...